Summary
In coagulation and fibrinolysis, kinetic data are difficult to obtain with ordinary
quantitative methods because no simple means are available to stop the reaction before
the determination of the activity formed.
This work describes how to calculate, from the data recorded, the amount of activity
at the moment the determination is started.
A formula is given for a zero, a first and a second-order reaction.
The method is exemplified by urokinase activation of plasminogen into plasmin. The
determination of the plasmin activity is done by means of the lysis time method.